Quick Answer: What Happens To CSF In Meningitis?

What does high glucose in CSF indicate?

Chemical meningitis, inflammatory conditions, subarachnoid hemorrhage, and hypoglycemia also cause hypoglycorrhachia (low glucose level in CSF).

Elevated levels of glucose in the blood is the only cause of having an elevated CSF glucose level..

Why is glucose low in CSF in bacterial meningitis?

The reason for the reduced glucose levels associated with bacterial meningitis was believed to be the need for glucose as fuel by infiltrating immune cells in response to infection. However, the possibility that the bacteria itself could manipulate glucose concentrations in the brain had not been explored before now.

Is CSF clear with viral meningitis?

CSF results The CSF findings are more suggestive of viral meningitis given the clear appearance of the CSF, the mildly raised WCC (consisting mainly of lymphocytes), raised protein level and normal glucose. Further investigations including CSF PCR would be useful in identifying the specific causative virus.

What gender is most affected by meningitis?

Etiologies and clinical outcomes An urgent treatable etiology was most frequently diagnosed in males (26% vs. 15%, p<0.05) and this difference was driven by a higher proportion of cryptococcal meningitis cases in males (48% vs. 14%).

What does CSF look like in viral meningitis?

Typical findings are: elevated opening pressure, elevated protein and hypoglycorrhachia. The fluid appearance may be cloudy or turbid. The CSF leukocyte concentration is usually elevated with a neutrophilic pleocytosis.

What diseases can be found in spinal fluid?

A CSF analysis may include tests to diagnose:Infectious diseases of the brain and spinal cord, including meningitis and encephalitis. … Autoimmune disorders, such as Guillain-Barré Syndrome and multiple sclerosis (MS). … Bleeding in the brain.Brain tumors.

Why is CSF protein elevated in meningitis?

CSF protein Bacterial meningitis leads to a more permeable blood brain barrier (due to increased inflammation). Protein leaks into the subarachnoid space from the blood, resulting in markedly increased CSF protein levels.

What are the isolation precautions for viral meningitis?

Meningococcal meningitis patients should be placed on droplet precautions (private room, mask for all entering the room) until they have completed 24 hours of appropriate antibiotic therapy. Negative pressure ventilation is not required. Patients with pneumococcal or viral meningitis do not require isolation.

What is considered high protein in CSF?

EVALUATION. Spinal fluid protein concentration is usually moderately elevated, with concentrations in the 150 to 300 mg/100 mL range.

Does high protein in CSF mean MS?

Cerebral Spinal Fluid Studies Oligoclonal Immunoglobulin Bands can be identified in the CSF of MS patients via electrophoresis. The overall protein level is also slightly elevated – up to 0.1 g/L. Protein level can be higher if the patient is going through a marked relapse (i.e.,. severe optic neuritis).

Can you get meningitis from a lumbar puncture?

Iatrogenic meningitis (IM) is a rare complication of diagnostic and therapeutic lumbar puncture (LP).

What does protein in CSF indicate?

An abnormal protein level in the CSF suggests a problem in the central nervous system. Increased protein level may be a sign of a tumor, bleeding, nerve inflammation, or injury. A blockage in the flow of spinal fluid can cause the rapid buildup of protein in the lower spinal area.

How do people get meningitis?

Bacteria that enter the bloodstream and travel to the brain and spinal cord cause acute bacterial meningitis. But it can also occur when bacteria directly invade the meninges. This may be caused by an ear or sinus infection, a skull fracture, or — rarely — some surgeries.

Where is meningitis most commonly found?

Meningococcal disease occurs worldwide, with the highest incidence of disease found in the ‘meningitis belt’ of sub-Saharan Africa.