Quick Answer: What Happens If You Stop Taking Clopidogrel?

How long does it take for clopidogrel to get out of your system?

by Drugs.com After a single, oral dose of 75 mg, Plavix (clopidogrel) has a half-life of approximately 6 hours.

It takes 5.5 x half-life of a medicine for it to be out of one’s system, therefore Plavix should be eliminated from your system in 5.5 x 6 = 33 hours..

Is there an alternative to clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

Can I drink coffee with clopidogrel?

Conclusions. Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

Is clopidogrel better than aspirin?

In summary, clopidogrel appears to be somewhat more effective than aspirin if one is willing to accept the unitary atherosclerosis paradigm. The gain, however, is modest: about 200 patients should use clopidogrel rather than aspirin for 1 year to prevent just one vascular event.

Does clopidogrel cause tiredness?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

Can you stop taking Plavix abruptly?

You do not need to wean the drug, and can stop it abruptly.

Is it safe to stop clopidogrel after one year?

Contrary to some recent reports indicating a full 12 months of dual antiplatelet therapy following percutaneous coronary intervention (PCI) is unnecessary, a large Danish registry study shows that halting clopidogrel after 1 year raises the risk of death and reinfarction in myocardial infarction (MI) patients.

Is it safe to take clopidogrel long term?

Safety Announcement [ 11-06-2015 ] A U.S. Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death in patients with, or at risk for, heart disease.

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

What are the side effects of clopidogrel 75 mg?

Common side effects of clopidogrel can include:headaches or dizziness.nausea.diarrhoea or constipation.indigestion (dyspepsia)stomach ache or abdominal pain.nosebleeds.increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).