- Why was nizatidine discontinued?
- Why was AXID discontinued?
- How fast does nizatidine work?
- Can nizatidine affect blood pressure?
- Is ranitidine the same as nizatidine?
- What is nizatidine generic for?
- What is the safest acid reflux medicine?
- What is the brand name for nizatidine?
- Is nizatidine still available?
- What is an alternative to Zantac?
- Does nizatidine cause weight gain?
- When should I take nizatidine?
Why was nizatidine discontinued?
Nizatidine Oral Solution is being recalled due to potential N-Nitrosodimethylamine (NDMA) amounts exceeding the levels established by the FDA.
Risk Statement: NDMA is classified as a probable human carcinogen (a substance that could cause cancer) based on results from laboratory tests..
Why was AXID discontinued?
Axid and Darvon are some of the products manufactured in Building 100. Product recalls for Axid (May 1988) and Darvon (June 1988) due to dissolution failures led to FDA’s inspection of the facility. In October, Lilly withdrew seven lots of Axid 150 mg pulvules because a manufacturing process did not ensure stability.
How fast does nizatidine work?
Absorption of nizatidine after oral administration is rapid and peak plasma concentrations (700 – 1800 ng/ml after 150 mg; 1400 – 3600 ng/ml after 300 mg dose) are usually achieved within two hours of administration (range 0.5 – 3 hours).
Can nizatidine affect blood pressure?
Stroke volume and blood pressure were not altered by nizatidine and/or pirenzepine. By contrast, heart rate and cardiac output significantly (P < 0.05) decreased in a dose-dependent manner 1.5 and 3 h after administration of 300 and 600 mg nizatidine.
Is ranitidine the same as nizatidine?
Nizatidine, administered as a 300 mg nocte and as a 150 mg b.d. dose appeared to be a safe H2 antagonist and was as effective as ranitidine in the treatment of duodenal and gastric ulceration.
What is nizatidine generic for?
Axid (nizatidine) Capsules are a histamine antagonist indicated for up to 8 weeks treatment of active duodenal ulcer. In most patients, the ulcer will heal within 4 weeks. Axid is available in generic form.
What is the safest acid reflux medicine?
If you have mild reflux symptoms that occur less than two times a week, you can start with a low dose of famotidine (Pepcid) or cimetidine (Tagamet).
What is the brand name for nizatidine?
Nizatidine is a histamine H2 receptor antagonist that inhibits stomach acid production, and is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. It was patented in 1980 and approved for medical use in 1988. It was developed by Eli Lilly. Brand names include Tazac and Axid.
Is nizatidine still available?
The Axid brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is an alternative to Zantac?
The following proton pump inhibitors are FDA-approved and may be appropriate Zantac alternatives for treating heartburn, depending on the advice of your doctor: Esomeprazole (brand name Nexium) Lansoprazole (brand name Prevacid) Omeprazole (brand name Prilosec)
Does nizatidine cause weight gain?
Weight gain is associated with treatment with olanzapine and other psychotropic agents. Nizatidine, a histamine H-2 receptor antagonist, has been proposed to have weight-reducing effects.
When should I take nizatidine?
Nizatidine comes as a tablet and capsule to take by mouth. It usually is taken once daily at bedtime or twice a day with or without food. Follow the directions on the package or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.